What to Do When Frontline Fails: 8 Effective Methods

Frontline is a widely used and highly effective topical medication for killing adult fleas on cats and dogs. However, there are instances where Frontline may not fully eliminate the flea problem. In such cases, it’s essential to explore alternative methods to address the issue effectively. Let’s take a look at some great methods to try when Frontline doesn’t work.

Reapplication of Frontline

If you notice that Frontline isn’t working as expected, the first step is to check when you last applied the medication. Over time, the effectiveness of Frontline diminishes. If it has been more than three weeks since the last application, it’s likely that the fleas are present because the medication is starting to wear off. In such cases, it’s advisable to talk to your vet about moving up your next treatment date.

Flea Bath

While Frontline is an excellent flea and tick preventative, relying solely on one medication may not provide comprehensive protection. Giving your pet regular flea baths with a flea-killing shampoo is a helpful and easy way to combat fleas when Frontline doesn’t work. However, remember that flea baths only alleviate live fleas and do not treat flea eggs. It’s crucial to incorporate flea baths as part of a broader approach to flea control.

Essential Oils

Many pet owners turn to essential oils as natural flea repellents. Essential oils with fragrances that repel fleas can be used alongside Frontline and regular flea baths to provide additional protection for your pets. However, it is vital to dilute essential oils properly and always check with your vet before using them on your pets. Some essential oils can be toxic if not diluted correctly. Tea tree oil, peppermint oil, citronella oil, rosemary oil, eucalyptus oil, neem oil, and coconut oil are effective options against fleas.

See also  Malocclusions in Cats: Understanding Misaligned Teeth

Flea Collars

Using flea collars is another effective approach to protect your pets from fleas. There are various prescription and over-the-counter flea collars available, with Seresto being one of the most proven and popular brands. Flea collars provide more extended protection against fleas compared to Frontline, lasting anywhere from three months to a year. Just ensure that your pet doesn’t chew their collar off.


Regularly combing your pet with a flea comb is an effective method to remove live fleas, flea dirt, and flea eggs. While combing does not kill fleas, it helps to control the infestation. Some experts recommend dipping the comb into freshly squeezed lemon juice before combing, as the acidity repels and kills fleas.


For a non-direct method of killing fleas, you can use small sachets in your pet’s sleeping area. Fill the sachets with cedar chips, lemon peel, and dried lavender buds. While effective, these sachets need to be replaced regularly as the potency of the ingredients diminishes over time.

Doctor Your Pet’s Food and Water

If your pet is not responsive to topical treatments or has a strong aversion to certain products, you can try adding vinegar or Brewer’s yeast to their food and water. Vinegar repels fleas when added in small amounts to your pet’s drinking water. Brewer’s yeast not only repels fleas but also improves your pet’s overall health.

Deep Clean

To effectively eliminate fleas, it’s essential to treat your home and yard in addition to your pet. Washing your pet’s bedding and any soft fabrics they come into contact with is crucial. Tumble drying these items on high heat can kill fleas in all life stages. Vacuuming your home, especially with a water-based cleaning system, and using steam cleaners on furniture and carpets can help eliminate fleas. Additionally, using baking soda or salt on surfaces that cannot be machine washed can dehydrate and kill fleas.

See also  Cat Diarrhea and Vomiting: Understanding the Causes and When to Seek Emergency Care

In conclusion, if Frontline doesn’t work as expected, there are several effective methods to address the issue. By incorporating flea shampoos, essential oils, flea collars, combing, deep cleaning, and other preventive measures, you can achieve a healthy, flea-free home for your pets. Remember to consult with your vet to determine the best approach for your specific situation. For more information on pet care and flea prevention, visit Katten TrimSalon.